Ultrafast Structural Dynamics of Molecular and Biomolecular Systems

  • PC Department Seminar
  • Date: May 22, 2023
  • Time: 11:00 AM (Local Time Germany)
  • Speaker: Henrike Müller-Werkmeister
  • Uni Potsdam
  • Location: Building G
  • Room: 2.06
  • Host: Alexander Paarmann
Ultrafast Structural Dynamics of Molecular and Biomolecular Systems
Observing molecular dynamics experimentally with both, highest spatial and temporal resolution is one of the biggest challenges in chemistry and biochemistry. Understanding and resolving structure-dynamics relationships will help to further understand molecular function. Few experimental methods allow to resolve multi-scale dynamics and structural information in the same experiment.

2D-IR spectroscopy can be performed as table-top experiment in solution state. Inhomogeneities of molecular ensembles are accessible and can be resolved by 2D-IR. Current research in our group targets photocatalysis, photochemistry and solvation dynamics in biomolecular systems.
While 2D-IR is an extremely powerful method to investigate biomolecules in solution, it doesn’t provide full atomic resolution. Ultrafast Electron diffraction and time-resolved X-ray diffraction at XFELs and synchrotrons in contrast can access structural dynamics with atomic resolution. I will highlight results from recent ultrafast electron diffraction experiments on Fe(II)-Spincrossover experiments and time-resolved serial crystallography of an enzymatic reaction.

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